There is endless debate about the best way to lose weight. I think you already know that there is no answer to this question yet. I suspect that in the future we will be able to determine the “best” diet for you as an individual, and it will probably depend on your gut microbiome and genetics. While there is ongoing research on these topics, from a practical standpoint this we can’t use this info yet1There are companies selling genetic testing kits that claim to tell you this information, but I would be very skeptical at this point whether the information is valid.


Regardless of what type of diet you follow and what type of research breakthroughs we learn in the future, there will remain 2 truths about losing weight: 
1. To lose weight, you need a caloric deficit. 
2. To sustain weight loss, you have to change your diet permanently. 

In light of these 2 truths, I have built my nutrition recommendations on the following concepts. 

  1. Your total daily energy expenditure determines how many calories you can eat
  2. You should track calories when you start your weight loss plan in order to “prove” that you have created an adequate calorie deficit to cause the desired rate of weight loss
  3. During the first few weeks of your diet overhaul, you should make a list of recipes and foods that fit your plan.
  4. As the weeks progress, you must develop the habit of eating foods that fit on your plan. Once you have the hang of your new normal, you can transition away from calorie counting. 

Creating a Caloric Defecit

Have you ever felt that you eat less than other people, yet you cannot lose weight? The problem almost certainly lies in that you aren’t restricting your food intake far enough below your total daily energy expenditure to trigger weight loss. Total daily energy expenditure is the number of calories your body burns in a day, including sleep and exercise. The most accurate way in a routine clinical setting to determine your total daily energy expenditure is to use indirect calorimetry. However, this can be expensive and is not routinely available in most clinics. A far cheaper and quicker method is to use a predictive energy expenditure equation (commonly referred to as a “metabolic calculator).  The metabolic calculator I use is Mifflin St. Jeor. These equations are not perfect, but they get pretty darn close to estimating what your body burns in a day. 



Potential errors when using metabolic calculators

  1. These formulas assume that people of the same gender, age, height, and weight have the same resting metabolic rate, which isn’t true. 2 people of identical gender/age/height/weight could have different amounts of muscle, and would therefore have slightly different metabolic rates.
  2. Repeated weight loss attempts have the effect of decreasing your metabolic rate. Metabolic calculators do not take this into account
  3. Metabolic calculators typically try to integrate how much exercise people perform. however, many people unwittingly overestimate how much exercise they do, which artificially inflates their calculated daily energy expenditure.

    Because these calculators are imperfect, we treat them as a guideline and a place to start. If a calculator predicts 1 pound of weight loss at 1200 calories a day but you are not losing weight at 1200 calories per day, then you modify the calorie goal downward by 100-200 calories and try again. 

Counting calories

If you were opening a business you would track your expenses and revenue, right? You could just wing it and hope to make money, but you probably wouldn’t stay in business very long. 

Overhauling your lifestyle with the goal of permanent weight loss is very, very hard. If you want to succeed, you need a way of auditing your diet so that you can tell what is working. If you are hitting calorie goals and your weight is stagnant, then either you are not counting correctly or your metabolic rate is lower than predicted and you should cut your caloric intake another 10%

You will not be counting calories forever, you should do it until you reach your goal. 

Smartphones have made tracking food intake far easier than ever before, with apps having enormous databases of foods to make counting easier. Popular examples include myfitnesspalcarb manager, and myplate


How many meals should I eat?

Most people who have trouble with excess weight should be eating 2 meals per day, if they can do so comfortably and without having to resort to frequent snacking. Your lifestyle will dictate which 2 meals you eat. There are some people who will feel awful if they don’t eat 3 times per day. You know who you are. If you need to eat 3 meals, by all means, do so. 

You may be thinking, “but I was told I should eat 5 or 6 small meals a day”. Some nutrition and exercise professionals will still make this recommendation, with the idea that this helps optimize the resting metabolic rate. Studies have not backed up this theory (Reviewed here). In theory, “small frequent meals” would be fine if one could also achieve a caloric deficit. If you can eat this often and achieve a calorie deficit, then I do not have a problem with it. But… most people will fail miserably on such a diet because *what* you have to eat is boring and limited. Eat half a cucumber and a hard boiled egg? No thanks. 

As I mentioned above, most people will be able to lose more weight and keep it off if they can master reducing meal frequency to 2 meals per day, and minimize snacking in-between. If you need to eat 3 meals, that is OK too (it’s just a little trickier).

Is it OK to skip breakfast?

Yes. The evidence does not support the notion that you must eat breakfast. A meta-analysis of 13 clinical trials did not show any weight loss benefit to eating breakfast. Instead, people who were assigned to eat breakfast actually consumed about 260 more calories per day compared to subjects who were assigned to skip breakfast. 

Does it matter what time of day I eat?

LC Ruddick Collins, et al. The Big Breakfast Study: Chrono‐nutrition influence on energy expenditure and bodyweight. Nut Bull 2018

The short answer is that we don’t know. This has been talked about more over the past decade due to research in circadian rhythms. Nearly every gene in our body involved in metabolism is partially regulated by CLOCK genes, which are in turn regulated by light-dark cycles from our environment. We call this the circadian (24 hour) timing system. Here is a neat review article on circadian rhythms if you want to learn more. Some animal studies show that timing food consumption to the early part of the waking period can be associated with favorable metabolic parameters. However, I am not aware of any proof in humans that timing meals in accordance with this has a meaningful benefit to your health. And furthermore, modern human societies are not primed to eat the largest meal in the morning and smallest meal in the later afternoon/early evening. So even if there was proof that there was a benefit to shifting most food consumption to the morning, would this be implementable from a practical standpoint?

Your diet needs to be forever

Unfortunately, unless you can stick to your diet forever, regaining weight is expected. It appears there are 2 mechanisms at the heart of weight regain metabolic adaptation and neurohormonal changes to appetite. 

1. Metabolic adaptation
Weight loss is associated with a slowing of resting metabolic rate that is greater than what we expect changes in body composition. This phenomenon is called metabolic adaptation, and it acts to counter weight loss. Sadly, metabolic adaptation lasts for YEARS. This has been demonstrated in the famous “Biggest Loser” study, where researchers evaluated contestants from the biggest loser at the beginning of the competition, at the end of the 30 week competition, and 6 years after the competition. The contestants lost 127 +/- 55 pounds after 30 weeks. Their baseline resting metabolic rate was 2606 +/- 649 calories per day, which decreased to 1996 +/-358 calories at the end of the competition. 6 years later, despite the contestants gaining most of the weight back, the average resting metabolic rate did not significantly change (1903 +/- 466 calories). Overall, the average resting metabolic rate was about 500 calories per day lower than one would have predicted based off their body size and age.  

2. Neurohormonal changes to appetite control
Weight loss is associated with increased appetite, as well as changes in hormones that have been shown to regulate appetite. An often-cited study published in 2011 demonstrated changes in appetite-regulating hormone associated with weight loss. The patients had lower leptin, peptide YY, amylin, CCK (hormones that decrease appetite) and higher ghrelin, GIP, pancreatic polypeptide (hormones that increase appetite). Alarmingly, these changes persist for at least 5 years. 

It would be nice if you could just be aggressive in dieting, then coast once you hit your goal weight. But with metabolic adaptation, your slowed metabolic rate will cause you to regain the weight if you revert to a diet even somewhat close to what you were eating at baseline. And since your metabolic rate is now lower, losing the weight again will be even harder (you may have experienced that it gets harder to lose weight after you regain it)

Calorie Counting won't work forever

While calorie counting absolutely works in the short term, I don’t believe it is the path to long-term success because it is just too much work. As I mentioned earlier, most of the popular diets show similar efficacy with regard to weight loss, and they all generate a caloric deficit. I recommend calorie counting as it is the ultimate way to ensure a calorie deficit.  
However, is not realistic to think you can keep calorie counting indefinitely. Just like with any diet, there are times when motivation wanes and life gets in the way of the rules you set up for your diet. At some point, you have to develop habits that make eating the right thing the easiest, default choice. 

Key habits for long term weight loss

  1. Finding a list of meals that fit within your calorie goals. People tend to eat the same things. You need about 3-4 breakfast options, 5-10 lunch options, and 10-15 dinner options that fit under your calorie threshold for weight loss. 
  2. Keeping healthy snacks stocked in the house
  3. Planning meals for the week in advance
  4. Shopping for the meal ingredients on the weekend/days off. This avoids the scenario of “we’re all out of food, let’s go eat out”.
  5. Keeping the house free of the foods you should be avoiding
  6. Integrating some exercise into your daily routine.

The rationale and evidence behind habit-forming is something I am still learning about and that I have trouble explaining still. I’m reading Good Habits, Bad Habits by Wendy Wood and The Diet Trap Solution by Judith Beck. I will continue to expand this section as I learn more.